Protein Labeling Reagents
Biotium CD28(204.12), CF568 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
eMolecules 25535-16-4 | Medchem Express | Propidium (Iodide) | 10mg | 446274299 | HY-D0815 | MFCD00011921 | 668.406 | C27H34I2N4
Medchem Express | W-7 (hydrochloride) | 25mg | 536983735 | HY-100912 | 61714-27-0 | MFCD00012559 | 377.320 | C16H22Cl2N2O2S
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Biotium Fascin-1(FSCN1/418), CF488A conjugate, 0.1mg/mL
Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection o
Biotium CD28(C28/74), CF568 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
eMolecules Carboxyrhodamine 110-PEG3-Azide | 1536327-95-3 | | 100mg
Broadpharm | Carboxyrhodamine 110-PEG3-Azide | 100mg | 268505038 | BP-22478 | 95.000 | 1536327-95-3 | | 574.594 | C29H30N6O7
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![eMolecules 197306-80-2 | BDP TR X NHS ester | Broadpharm634.460 | C31H29BF2N4O6S | 0.000 | F[B-]1(F)n2c(ccc2-c2ccc(OCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)cc2)C=C2C=CC(c3cccs3)=[N+]12 | 1mg | 761705583](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502459511.PNG-250.jpg)
eMolecules 197306-80-2 | BDP TR X NHS ester | Broadpharm634.460 | C31H29BF2N4O6S | 0.000 | F[B-]1(F)n2c(ccc2-c2ccc(OCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)cc2)C=C2C=CC(c3cccs3)=[N+]12 | 1mg | 761705583
BDP TR X NHS ester | Broadpharm | 197306-80-2634.460 | C31H29BF2N4O6S | 0.000 | F[B-]1(F)n2c(ccc2-c2ccc(OCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)cc2)C=C2C=CC(c3cccs3)=[N+]12 | 1mg | 761705583
Biotium CD45 / LCA(2B11 + PD7/26), CF488A conjugate, 0.1mg/mL
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. This MAb reacts with all isoforms of CD45R expressed by all hematopoietic cells, except erythrocytes, having a higher level of expression on lymphocytes than on granulocytes (Workshop IV). Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplas
Lumiprobe Sulfo-Cyanine7.5 NHS ester, 5 mg
Sulfo-Cyanine7.5 is a near infrared water soluble and hydrophilic dye for the NIR imaging applications.
(F)F.CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCc3ccc(cc3)-c3nnc(C)nn3)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 5mg | 374905208](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502513205.JPG-250.jpg)
eMolecules 2183473-57-4 | Cy3 methyltetrazine | Broadpharm727.660 | C40H46BF4N7O | 98.000 | F[B-](F)(F)F.CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCc3ccc(cc3)-c3nnc(C)nn3)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 5mg | 374905208
Cy3 methyltetrazine | Broadpharm | 2183473-57-4727.660 | C40H46BF4N7O | 98.000 | F[B-](F)(F)F.CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCc3ccc(cc3)-c3nnc(C)nn3)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 5mg | 374905208
Medchemexpress LLC Xeruborbactam disodium | 2170848-99-2 | 99.0% | 283.96 | 5 MG
Xeruborbactam disodium | 2170848-99-2 | 99.0% | 283.96 | 5 MG
(=O)=O)c4ccc(cc4C3(C)C)[S-](=O)(=O)=O)=C2c2ccc(CCC(=O)NCC#C)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 795361753](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465544.JPG-250.jpg)
eMolecules Tetrasulfo-Cy7-Alkyne | Broadpharm |1010.220 | C48H55N3O13S4 | 0.000 | CC1(C)\C(=C/C=C2\CCCC(\C=C\C3=[N+](CCCS(O)(=O)=O)c4ccc(cc4C3(C)C)[S-](=O)(=O)=O)=C2c2ccc(CCC(=O)NCC#C)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 795361753
Tetrasulfo-Cy7-Alkyne | Broadpharm |1010.220 | C48H55N3O13S4 | 0.000 | CC1(C)\C(=C/C=C2\CCCC(\C=C\C3=[N+](CCCS(O)(=O)=O)c4ccc(cc4C3(C)C)[S-](=O)(=O)=O)=C2c2ccc(CCC(=O)NCC#C)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 795361753
Biotium CD20(B9E9), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentia
Biotium Cyclin D1(DCS-6), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescenc